We develop novel and differentiated oral small molecule therapies for patients suffering from diseases with significant unmet medical need
We are a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of patients with significant unmet medical needs in the areas of fibrosis, lysosomal storage disorders and oncology.
We have built a pipeline backed by a discovery engine with an extensive library of proprietary molecules, a wholly-owned research and development facility and a team with significant expertise and deep experience in the development of compounds that target nuclear receptors, transcription factors and epigenetic modulation. By leveraging these assets and expertise, we are advancing two clinical candidates in two indications, as well as a deep pipeline of earlier stage programs.
Research Areas & Pipeline
With many potential new therapies that are currently in clinical trials, our goal is to be the industry leader in developing drugs that interact with nuclear receptors, transcription factors and epigenetic modulators.
Lanifibranor, our lead product candidate, is an anti-fibrotic treatment acting on the three PPARs (peroxisome proliferator-activated receptors), which plays a key role in controlling the metabolic, inflammatory and fibrotic processes. We are investigating lanifibranor for the treatment of NASH/MASH, a severe and increasingly prevalent liver disease that is already affecting over 30 million people in the United States.
